The Piazza Grande in Arezzo is the heart of this charming city and one of Tuscany’s most picturesque squares. Surrounded by notable Renaissance architecture, including the Palazzo delle Logge designed by Giorgio Vasari, the square is remarkable for its sloping layout and the seamless blend of buildings from different periods.

Santa Maria della Pieve is a church in Arezzo, Tuscany, central Italy.

The Clock Tower in Arezzo, located on the Piazza Grande, is accessible through the Palazzo di Fraternita dei Laici. This tower is renowned for its astronomical clock, among the oldest functioning clocks in Italy, created in 1552 by the master watchmaker Felice di Salvatore da Fossato. The clock is part of a facade designed by Giorgio Vasari, featuring a unique system that includes three bells managed through complex mechanisms. This clock offers not only the time but also astronomical data, according to the Ptolemaic conception of the universe.

Arezzo Cathedral is a Roman Catholic cathedral in the city of Arezzo in Tuscany, Italy. It is located on the site of a pre-existing Palaeo-Christian church and, perhaps, of the ancient city's acropolis.

The Basilica of San Francesco is a late Medieval church in Arezzo, Tuscany, Italy, dedicated to St Francis of Assisi. It is especially renowned for housing in the chancel the fresco cycle Legends of the True Cross by Piero della Francesca.

The Basilica of San Domenico is a Gothic-style church located in Arezzo. It is dedicated to St. Dominic and is particularly renowned for containing a painted crucifix by Cimabue from 1265. This piece is noted for its historical importance due to Cimabue's stylistic innovation; he deviated from the Byzantine conventions of his time, introducing greater expressionism with themes of death, empathy, and humanism. The basilica itself was constructed between the 13th and 14th centuries, characterized by a sober and minimalistic architectural style.

Step into the world of the famous Renaissance artist and architect Giorgio Vasari (1511-1574). His accomplishments include designing the tomb of his friend, Michaelangelo as well as the loggia of the Palazzo degli Uffizi in Florence and the passage that connects the Uffizi with the Palazzo Pitti. He was also made Knight of the Golden Spur by the Pope. Vasari built his residence in 1547 himself and today this museum showcases Vasari’s works and provides insight into his life. Explore the art-filled rooms and gain a deeper understanding of the Renaissance period in Arezzo. Note: The museum is closed on Tuesdays.

The Badia delle Sante Flora e Lucilla or Abbey of Saints Flora e Lucilla is a Medieval abbey in Arezzo, Tuscany, Italy.

Santa Maria delle Grazie is a church in Arezzo, Tuscany, central Italy. It is located on the site of an ancient sanctuary with a spring that, in the Etruscan-Roman era, it was consecrated to Apollo. In the Middle Ages it was known as Fonte Tecta. In 1425, Saint Bernardino of Siena tried in vain to have it destroyed. Ousted from the city, he returned in 1428 and, this time, he was able to obtain the replacement of the spring with an oratory. Here, from 1428 and 1431, Parri di Spinello, son of Spinello Aretino, painted a fresco with the Madonna of Misericordia, now inserted in the marble altar by Andrea Della Robbia. The altar portrays, in the tympanum, a Madonna with Child between two Angels; in the niches are the saints Laurentinus, Pergentinus, Donatus and Bernardino, while the paliotto has a Pietà. Around 1490, the oratory received a portico, designed by Benedetto da Maiano. The structure was inspired by Filippo Brunelleschi's Ospedale degli Innocenti. On the longest side it has seven arcades with medallions, on a basement with steps.

The Diocesan museum of sacred art in Arezzo was founded in 1963 but opened regularly to the public only in 1985, and was housed in several rooms above the sacristy of the Cathedral of San Donato. In 2011 it was relocated to the first floor of the bishop's residence. The museum exhibits works of art and liturgical items, from the 12th to the 19th centuries, that come from the cathedral and other churches in the diocesan territory, significant for their religious and cultural significance to Arezzo and the surrounding area. Highlights of the museum include several works of Giorgio Vasari and the Pace di Siena. The museum is accessible to the disabled, offers space for teaching, temporary exhibitions, and restoration.